“I thank the Chen Immigration team for all their help with my application. They were especially patient with the many questions I had with my application as my employment status changed when I took a brief career break due to personal circumstances. I will be retaining their services if I decide to file further petitions in the future.”

Case Summary:      

When the Client first set out on the path of biomedical research, the vision was clear: to uncover the molecular blueprints that could transform the way humanity diagnoses and treats devastating diseases. With a Ph.D. in physiology and biophysics, Client has steadily built a career centered on exploring the intricate world of cell signaling pathways, with the ultimate goal of developing new drug targets and diagnostic tools for conditions such as Alzheimer’s disease and cancer.

This endeavor is not only scientifically ambitious but also of pressing national importance. By characterizing how cells communicate and how these pathways go awry, Client’s research lays the foundation for precision therapies that could significantly improve public health outcomes in the United States.

Over the years, Client has published 11 peer-reviewed journal articles (5 first-authored) and 2 preprints (1 first-authored), which collectively have been cited more than 200 times according to Google Scholar. Such recognition demonstrates that Client’s findings are being actively utilized by peers worldwide, advancing new avenues of inquiry in the biomedical sciences. Beyond publications, Client has also been entrusted with at least 8 peer review assignments, a responsibility reserved for experts whose judgment and expertise are held in high regard.

Importantly, Client’s work has attracted the backing of major national funding sources, including the National Institutes of Health and the National Science Foundation, both of which direct support toward projects with significant societal benefit. This funding serves as further evidence that Client’s research is not only scientifically sound but also aligned with national priorities in healthcare innovation.

The strength of the Client’s case was further bolstered by four recommendation letters from distinguished experts in the field, each attesting to the originality, influence, and broad applicability of the research.

“Having expanded the medical field’s understanding of cataracts through research that involved advanced microscopy techniques, he has established himself as an irreplaceable asset to U.S. healthcare and medicine.”

Despite the rigorous scrutiny of the NIW process, including the challenge of demonstrating substantial merit and national importance under the Dhanasar framework, USCIS agreed that Client’s contributions and proposed endeavors met the high standard required.

On September 2, 2025, Client’s I-140 National Interest Waiver petition was approved, following its filing on February 12, 2024. This approval is not just a recognition of past accomplishments but also an affirmation of the Client’s future potential to continue advancing biomedical science for the benefit of the United States and beyond.